Neurological research

There is much interest in the use of hyperbaric oxygen therapy as a treatment for neurological conditions. Current ongoing research includes:

  • A study, sponsored by Intermountain Health Care, collaborating with the Deseret Foundation, of hyperbaric oxygen therapy in chronic stable brain injury, in order to discover the feasibility of conducting clinical research in individuals with chronic sequelae following brain injury who are given hyperbaric oxygen.102
  • A study, sponsored by the International Hyperbaric Medical Foundation, to research  hyperbaric oxygen therapy in chronic traumatic brain injury or post-traumatic stress disorder, specifically to confirm in large numbers of study participants at multiple sites nationwide, the strong positive results obtained in pilot studies.103
  • A study, sponsored by San Antonio Military Medical Center, of the treatment of traumatic brain injury with hyperbaric oxygen therapy, hoping to determine whether hyperbaric oxygen therapy improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury.104
  • A study, sponsored by Assaf-Harofeh Medical Center, of the effect of hyperbaric oxygen therapy on patients suffering from neurologic deficiency due traumatic brain injury, hoping to evaluate the effectiveness of HBOT in the treatment of chronic mild traumatic brain injuries.105
  • A study, also sponsored by Assaf-Harofeh Medical Center, of the effect of hyperbaric oxygen on patients suffering from neurologic deficiency due to stroke, hoping to evaluate the effect of HBO therapy on patients suffering from chronic neurological deficient due to stroke.106
  • A study, sponsored by Intermountain Health Care collaborating with the Deseret Foundation, of functional and anatomical magnetic resonance imaging (MRI) of chronic brain injury and hyperbaric oxygen study subjects, in order to evaluate brain MRI and Brain CT (Computed Tomography) Angiogram data in subjects who participate in the “Hyperbaric Oxygen for Chronic Stable Brain Injury.”   Including information from MRI and CT studies provide information about whether hyperbaric oxygen improves brain function in subjects who have had a brain injury.107
  • A study, sponsored by the Virginia Commonwealth University collaborating with the United States Naval Medical Center, and Portsmouth Hunter Holmes Mcguire Veteran Affairs Medical Center, of hyperbaric oxygen therapy for post-concussive symptoms after mild traumatic brain injury, hoping to serve as a demonstration project to determine the tolerability of individuals with persistent post-concussive symptoms from combat-related mild traumatic brain injury, identify dose-finding for hyperbaric oxygen therapy, and determine the efficacy of said therapy.108

Recently completed studies include:

  • A comparison, sponsored by the Minneapolis Medical Research Foundation, between different types of oxygen treatment following traumatic brain injury, which evaluated the use of hyperbaric oxygen therapy and 100% Fi02 separately and in combination.109

Notes
102http://www.clinicaltrials.gov/ct2/show/NCT00830453?term=hyperbaric+oxygen+therapy&rank=15
103http://www.clinicaltrials.gov/ct2/show/NCT01105962?term=hyperbaric+oxygen+therapy&rank=21
104http://www.clinicaltrials.gov/ct2/show/NCT00810615?term=hyperbaric+oxygen+therapy&rank=23
105http://www.clinicaltrials.gov/ct2/show/NCT00715052?term=hyperbaric+oxygen+therapy&rank=28
106http://www.clinicaltrials.gov/ct2/show/NCT00715897?term=hyperbaric+oxygen+therapy&rank=42
107http://www.clinicaltrials.gov/ct2/show/NCT01126515?term=hyperbaric+oxygen+therapy&rank=60
108http://clinicaltrials.gov/ct2/show/NCT01220713?cond=%22Hyperbaric+Oxygenation%22&rank=23
109http://www.clinicaltrials.gov/ct2/show/NCT00170352?term=hyperbaric+oxygen+therapy&rank=56