Surgical and Pharma-Therapeutics research

Another area of interest for those involved with hyperbaric oxygen therapy is its potential  usefulness as an additional surgical and pharma-therapeutic aid. Current research into these possibilities includes:

  • A study, sponsored by the Institute of Cancer Research in the United Kingdom, on hyperbaric oxygen therapy compared with standard therapy in treating chronic arm lymphedema in patients who have undergone radiation therapy for cancer, hoping to find how well hyperbaric oxygen works compared to standard therapy in treating chronic arm lymphedema in patients who have undergone radiation therapy for cancer.117
  • A study, sponsored by the Baromedical Research Foundation in collaboration with the Palmetto Health Richland, the Mayo Clinic, Dartmouth-Hitchcock Medical Center and Eastern Virginia Medical School, on dose escalation of hyperbaric oxygen with radiation and chemotherapy to treat squamous cell carcinoma of the head and neck, hoping to determine patient tolerance as well as feasibility of treatment delivery and acute toxicities associated with the treatment.118
  • A study, sponsored by Xijing Hospital, on hyperbaric treatment in trigeminal neuralgia patients, hoping to determine whether the hyperbaric oxygen treatment reduces pain and improve the life quality in trigeminal neuralgia patients.119
  • A study, sponsored by Rigshospitalet, Denmark, on hyperbaric oxygen treatment of mandibular osteoradionecrosis, hoping to determine whether hyperbaric oxygen therapy improves healing after surgical removal of necrotic bone in irradiated previous head and neck cancer patients.120

Recently completed studies:

  • A study, sponsored by Xijing Hospital, on preconditioning with hyperbaric oxygen in cardiovascular surgery, hoping to determine protective effect of hyperbaric oxygen preconditioning on brain and myocardium ischemia-reperfusion injury during coronary artery bypass graft surgery.121
  • A study, sponsored by Hull and East Yorkshire Hospitals NHS Trust in collaboration with North of England Medical and Hyperbaric Services, on the protective effects of treatment with hyperbaric oxygen prior to bypass heart surgery, hoping to determine whether treating patients who have coronary heart disease with hyperbaric oxygen prior to coronary artery bypass graft surgery reduces injury to the heart and vascular system during and after surgery.122

Notes
117http://clinicaltrials.gov/ct2/show/NCT00077090?cond=%22Hyperbaric+Oxygenation%22&rank=20
118http://www.clinicaltrials.gov/ct2/show/NCT00474825?term=hyperbaric+oxygen+therapy&rank=41
119http://www.clinicaltrials.gov/ct2/show/NCT00866424?term=hyperbaric&rank=6
120http://www.clinicaltrials.gov/ct2/show/NCT00760682?term=hyperbaric&rank=7
121http://www.clinicaltrials.gov/ct2/show/NCT00817791?term=hyperbaric+oxygen+therapy&rank=59

122http://www.clinicaltrials.gov/ct2/show/NCT00623142?term=hyperbaric&rank=5