Intracranial abscess of the brain tissue and the covering of the brain is common in AIDS patients and in “Third World” countries. Intracranial abscesses are almost always due to anaerobic infections, but the mode of action of HBOT is mainly through stimulation of the killing ability of white blood cells.
Treatment at 2.5 ATA for 90 minutes is started twice a day and then continued daily. An average of 12 to 15 treatments are given for an uncomplicated abscess; 40 to 60 treatments may be needed if accompanying osteomyelitis is present. No patients treated for intracranial abscess with HBOT have died; the mortality rate was 23% in cerebral abscess patients who received only surgical and antibiotic treatment.